Biochemistry November 10, 2006

                                              Biochemistry, 5th Edition, 2002-02

ISBN: 0716746840 |Title: Biochemistry, 5th Edition,
2002-02| Author: Jeremy M. Berg, John L. Tymoczko, Lubert Stryer
|Publisher: W. H. Freeman| pages: 1100| PDF 26.18 MB

Reviewer:

This is a superb book to understand the excitement in biochemistry and
to understand its relevance to human health. Stryer’s book presents
biochemistry in a completely different manner. Instead of traditionally
presenting one topic after the other, it presents each chapter giving a
representative molecule or system for explanation and characterization
of the material in that chapter . For example, heamoglobin and
myoglobin for explaining the three dimensional structure of proteins,
lysozyme and chymotrypsin for explaining enzyme action, and a host of
others. Each example is critically chosen, considering its role and
function in life and metabolism. This makes the matter very interesting
and practical. Paralleling this are given descriptions of diseases and
biochemical disorders as well as historical perspectives. The last
part, molecular physiology, gives a lucid exposition of the fundamental
biochemical processes in living organisms. In fact, the whole point of
view in the book is a physiological one. The book is unlike Lehninger,
which is essentially a traditional textbook. Even though Lehninger is
great as an introductory book, Stryer is, in my opinion, the book to
read if you want to learn biochemistry as a discipline which should be
viewed as an exciting excursion into human metabolism and life.

Review of new edition (Berg, Tymockzo):

I had written a favourable review earlier for a previous edition of
Stryer. I rest my case for the latest edition too. Jeremy Berg and John
Tymoczko, both accomplished authors, join Lubert Stryer in producing
this time tested and comprehensive book. If you are someone like me,
who believes that enzymes and proteins are the key to understanding the
mysteries of life, then this book is for you. While it may not have as
much coverage of nucleic acid chemistry biochemistry as some of the
other books, I believe that the next revolution in biology is going to
hinge upon our understanding of SYSTEMS. And while an understanding of
genes is crucial as enabling knowledge, if you really consider all the
actual action that happens in biochemical systems, almost all of it is
mediated by enzymes and receptors. Stryer’s new edition has literally
hundreds of pictures and discussions of proteins and enzymes which
explain the structure and function of these magnificent biological
agents. The book has still retained the concise and yet comprehensive
style which made its previous edition so good. Again, the book strikes
a good balance between textbook and medical biochemistry, which is its
great strength. Small boxes and side discussions throw light on the
most interesting events connected with drug metabolism and disease. As
a side point, the discussions about nucleic acid biology which the
authors HAVE included are pretty good in themselves. Biochemistry is
one of the most exciting branches of scientific research. This is
because first of all it is highly interdisciplinary, enjoying a
wonderful synergy with organic and inorganic chemistry, physical
chemistry and physics, and of course, biology. Secondly, Biochemistry
is an extraordinarily dynamic subject and biochemical knowledge doubles
every five years. Discoveries in biochemistry directly affect medical
science. In the 21st century, it continues to promise us radical
understanding into the working of life, and any good biochemistry book
should ideally convey this excitement to the reader. This one does. The
bottom line is, if you want to get excited about the miracle that is
called life, and want to do it in a rational way, Stryer is still one
of the very best. I hope it continues to be so.

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